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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPIL2
All Species:
6.67
Human Site:
S498
Identified Species:
14.67
UniProt:
Q13356
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13356
NP_680481.1
520
58823
S498
R
A
A
E
E
E
P
S
T
S
A
T
V
P
M
Chimpanzee
Pan troglodytes
XP_001168978
520
58777
S498
R
A
A
E
E
E
P
S
T
S
A
T
V
P
M
Rhesus Macaque
Macaca mulatta
XP_001088432
378
42947
S357
D
E
F
R
P
N
L
S
H
T
G
R
G
I
L
Dog
Lupus familis
XP_534768
523
59161
E498
A
T
K
R
V
A
E
E
E
P
S
T
S
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D787
521
59046
P498
K
R
S
A
E
E
E
P
S
T
S
T
A
T
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079584
521
59210
D498
A
T
K
R
S
A
E
D
D
E
A
G
P
S
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611113
517
58940
E493
Q
T
V
A
K
K
P
E
A
P
L
T
S
A
Q
Honey Bee
Apis mellifera
XP_623363
521
59810
E498
E
D
K
I
E
K
E
E
L
N
I
P
S
T
I
Nematode Worm
Caenorhab. elegans
P52012
523
58515
K498
A
V
N
K
R
Q
G
K
M
E
D
V
P
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJX0
595
65005
T562
S
S
T
A
T
K
D
T
K
G
S
L
D
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RXA6
597
65782
G548
G
G
G
G
P
K
V
G
K
Y
L
D
V
G
A
Conservation
Percent
Protein Identity:
100
99.8
66.9
92.3
N.A.
90.2
N.A.
N.A.
N.A.
N.A.
77.7
N.A.
N.A.
54
57
48.7
N.A.
Protein Similarity:
100
100
68.4
96.5
N.A.
95.9
N.A.
N.A.
N.A.
N.A.
88.8
N.A.
N.A.
73.4
72.9
65.3
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
100
20
13.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
33.3
26.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.7
N.A.
39.7
Protein Similarity:
N.A.
N.A.
N.A.
59.5
N.A.
55.6
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
19
19
28
0
19
0
0
10
0
28
0
10
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
10
10
10
0
10
10
10
0
10
% D
% Glu:
10
10
0
19
37
28
37
28
10
19
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
10
0
0
10
10
0
10
10
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
10
% I
% Lys:
10
0
28
10
10
37
0
10
19
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
10
0
19
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
19
% M
% Asn:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
19
0
28
10
0
19
0
10
19
19
10
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
19
10
0
28
10
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
10
0
10
0
0
28
10
19
28
0
28
19
0
% S
% Thr:
0
28
10
0
10
0
0
10
19
19
0
46
0
28
10
% T
% Val:
0
10
10
0
10
0
10
0
0
0
0
10
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _